Known exploited · Microsoft

CVE-2021-42321: Microsoft Exchange Server Remote Code Execution Vulnerability

What it is

An authenticated attacker could leverage improper validation in cmdlet arguments within Microsoft Exchange and perform remote code execution.

Added November 17, 2021Due December 1, 2021CISA KEV catalog 2026.10.01

Vendor
Microsoft
Product
Exchange
Added to KEV
November 17, 2021
CISA due date
December 1, 2021
Ransomware use
Known

What CISA requires

Apply updates per vendor instructions.

Forensic triage

No

What to do now

  1. Find every instance of Exchange you run, including the forgotten ones, and check its version against the vendor advisory.
  2. Apply the vendor's fix or mitigation, before December 1, 2021 if you are bound by CISA's deadline, sooner if it faces the internet.
  3. Assume it was tried against you already: look for signs of exploitation from the date it was added, not from the day you patched.
  4. Until every instance is patched, block the attack at the edge: a WAF in blocking mode stops Java deserialization payloads.

References

CVE-2021-42321 in the National Vulnerability Database

The Dome

Block it at the edge while you patch

The Dome's WAF runs the OWASP Core Rule Set in blocking mode and stops Java deserialization payloads before they reach your application.

See the Dome

T Academy

Train the engineers who fix it

Security engineering on real hosts in the browser, every objective checked on the machine. The first two lessons of Linux 1 are free.

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Source: CISA Known Exploited Vulnerabilities Catalog (public domain), catalog version 2026.10.01.